What is Hyaluronic acid(HA)?

Hyaluronic acid is a naturally ocurring polysaccharide molecule that acts like a biological sponge, capable of binding up to 1,000 times its own weight in water.

Where HA Works Its Magic in Your Body

In your Skin

1. Epidermis (Surface Layer) : HA creates a protective moisture film that prevents water loss, giving you that coveted “glass skin” look immediately after applying a hydrating serum.
2. Dermis (Deep Layer) : HA acts as a cushion around collagen and elastin fibers while helping to calm inflammation. This is where the long-term anti-aging benefits happen-smoother,bouncier skin that maintains its elasticity.

Beyond Skincare

Weight : Why Size Matters

Not all hyaluronic acid is created equal. The molecular weight (measured in kilodaltons or kDa) determines how deeply HA can penetrate your skin and what benefits you’ll see.

High Molecular Weight (>1,000 kDa)

• What it does: Forms a protective film on skin’s surface
• Benefits: Instant hydration and plumping effect
• Best for: Quick moisture boost, makeup prep
• Limitation: Can’t penetrate deeper skin layers

Medium Molecular Weight (100-500 kDa)

• What it does: Bridges surface and deeper skin layers
• Benefits: Balanced hydration that works both immediately and over time
• Best for: Daily use serums and essences
• 2025 trend: Multi-weight “5D” formulations combining several molecular sizes

Low Molecular Weight (<100 kDa)

• What it does: Penetrates through the stratum corneum into deeper skin layers
• Benefits: Anti-inflammatory properties, long-term skin improvement
• Best for: Sensitive or irritated skin, anti-aging treatments
• Research spotlight: Recent studies show low-MW HA actually reduces inflammation rather than causing it

Why HA Still Dominates the Skincare Market in 2025

Despite countless new ingredients launching each year – from bakuchiol to growth factors to peptide complexes-hyaluronic acid remains the undisputed champion of skincare. Here’s why HA continues to hold the #1 spot :

Universal Compatibility

HA plays well with literally everything. You can use it with retinol, vitamin C, AHAs, niacinamide, PCL , or any other ingredient without worry. This versatility makes it the ultimate “safe bet” for both skincare novices and ingredient-savvy enthusiasts.

Immediate + Long-term Results

Most skincare ingredients force you to choose : instant gratification or long-term benefits. HA delivers both.

You can see plumping and hydration within minutes of application, while the deeper molecular weights work on inflammation and skin structure over week and months.